Stem Cell Biology and Regenerative Medicine In Ophthalmology
1 The Eye as a Target Organ for Stem Cell Therapy . . . . . . . . . . . . . 1
Mark A. Fields, John Hwang, Jie Gong, Hui Cai,
and Lucian V. Del Priore
2 Stem Cells in Oculofacial Plastic Surgery . . . . . . . . . . . . . . . . . . . . 31
Bryan J. Winn and Mary Whitman
3 The Current Status of Corneal Limbal Stem Cell
Transplantation in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
Roy S. Chuck, Alexandra A. Herzlich, and Philip Niles
4 Lens Differentiation from Embryonic Stem (ES) and Induced
Pluripotent Stem (iPS) Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
Ales Cvekl, Ying Yang, Yang Jing, and Qing Xie
5 Stem Cells and Glaucoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Jonathan Hertz and Jeffrey L. Goldberg
6 Bone Marrow Stem Cells in Retinal Disease . . . . . . . . . . . . . . . . . . 99
Louis K. Chang
7 Stem Cells, Mechanism-Based Therapies and Regenerative
Medicine Approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 107
Xining He, Deniz Erol, and Stephen H. Tsang
8 New Developments in Retinal Cell Transplantation and the
Impact of Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121
Peter Gouras
9 Cancer Stem Cells in Uveal Melanoma . . . . . . . . . . . . . . . . . . . . . . 139
Helen Kalirai, Bertil E. Damato, and Sarah E. Coupland
10 Current Ex-Vivo Gene Therapy Technologies and Future
Developments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153
Chen-Hsien Su and Deniz Erol
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11 Stem Cell-Based Therapeutics in Ophthalmology: Application
Toward the Design of Clinical Trials . . . . . . . . . . . . . . . . . . . . . . . 171
Rony Gelman and Stephen H. Tsang
About the Editor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181
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